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Analyze the development of medical equipment battery technology

by:Vglory      2021-04-08
The development of medical device battery technology is the first implantable cardiac pacemaker application. Since 1960, a variety of active implantable medical device batteries have been widely used in the diagnosis and treatment of various diseases, such as Implantable cardiac pacemakers and defibrillators, various neurostimulators (including brain pacemakers, spinal cord stimulators, vagus nerve stimulators, sacral nerve stimulators and phrenic nerve stimulators, etc.), drug pumps, heart Electric recorder, etc. Implantable cardiac pacemakers, for example, there are more than 500,000 cardiac pacemakers implanted in the human body every year in the world [2]. Active devices are implanted in the human body for a long time. A key component is the power lithium ion battery. Under special implant application conditions, the battery must meet several important implantable medical equipment requirements: high safety and reliability, long life and stability, high energy density, etc. This article mainly analyzes the development history of batteries used in active implantable medical devices. In the early 1970s, lithium batteries were developed. Greatbatch founded Greatbatch in 1970, focusing on researching batteries for active implantation devices. He believes that batteries are the most important part of pacemakers and it is also a step forward. Research problem. Greatbatch company has obtained the patent license of lithium iodine battery technology, carried out further technical optimization, applied for a number of related patents, and applied it to cardiac pacemakers. In 1972, the first pacemaker powered by a lithium battery was implanted in the human body, using lithium iodine (Li/I2) batteries. The use of lithium batteries is a milestone in the active implantation of batteries, which solves the problems of battery reliability and long life. In the next few years, lithium batteries quickly replaced various batteries such as mercury oxide, and almost all implantable medical devices now use lithium batteries as a power source. In fact, until now, the lithium battery is still a low-power pacemaker. The most widely used battery, in addition to the iodine lithium battery, and various other lithium battery cathode materials are developed by application programs, including Li/Ag2CrO4 (lithium/ Silver chromate), Lee/SOCl2 battery (lithium/thionyl chloride battery, Lee/CuS (lithium/copper sulfide), Lee/summary battery (lithium/manganese dioxide battery, Lee/CFx battery (lithium/fluorocarbon) , The application prospects of lithium/SVO/silver vanadium oxide (lithium batteries) and other batteries in active implantable medical devices. The rapid development of active implantable medical devices will surely promote the continuous progress of implantable battery technology. On the one hand, lithium The application of batteries will have newer technologies and will continue to improve their overall performance in all aspects. On the other hand, they will continue to use new materials for battery solutions, such as the approval of St. Jude Medical’s electrodeless pacemaker NanostimCE in 2013, Its size is only Φ41.4 mm x 6 mm, which is one-tenth of the traditional pacemaker. Life is similar to that of traditional pacemakers. It uses disposable batteries. The patent mentions that Nanostim developed this pacemaker battery and BetaBatt developed DECTM. [24], the battery contains the radioactive element tritium. From the perspective of the need for further miniaturization of active implanted medical equipment, radionuclear fuel power cells may re-enter the market. There are also many reports on the research of microbial fuel power cells, Massachusetts Institute of Technology Invented implantable glucose fuel power battery[25], using silicon and platinum materials, through a standard semiconductor manufacturing process, implanted in the human body, using platinum as a catalyst, electrons decompose glucose molecules to generate electricity, which can generate 3.4mW /cm2 average power and peak power of 180mW/cm2, batteries may bring revolutionary changes to active implantable power supplies. The research on batteries that can be applied to active implantable medical devices is exciting and worth looking forward to. Statement: This site Some pictures and content of the published article are from the Internet, if there is any infringement, please contact to delete
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